WebJul 27, 2024 · Mechanical loading of the intervertebral disc (IVD) initiates cell‐mediated remodeling events that contribute to disc degeneration. Cells of the IVD, nucleus pulposus (NP) and anulus fibrosus (AF), will exhibit various responses to different mechanical stimuli which appear to be highly dependent on loading type, magnitude, duration, and anatomic … WebApr 11, 2024 · Therefore, we aimed to create a new nucleus replacement that replicates intact intervertebral disc biomechanics, and thus has the potential for clinical applications. Materials and methods: Two implants with an outer ring and one (D2) with an additional midline strut were compared. Static and fatigue tests were performed with an INSTRON …
Mechanical Initiation of Intervertebral Disc Degeneration
WebApr 21, 2024 · Abstract. Painful herniated discs are treated surgically by removing extruded nucleus pulposus (NP) material (nucleotomy). NP removal through enzymatic digestion is also commonly performed to initiate degenerative changes to study potential biological repair strategies. Experimental and computational studies have shown a decrease in … WebAug 20, 2024 · The effect of degenerative morphological changes of the intervertebral disc on the lumbar spine biomechanics: a poroelastic finite element investigation [J]. Fabio Galbusera, Hendrik Schmidt, Cornelia Neidlinger-Wilke, Computer methods in biomechanics and biomedical engineering . 2011,第7a9期 c-spine herniated disc c5/6 icd 10
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WebJan 1, 2024 · Severe Lumbar Intervertebral Disc Degeneration Is Associated with Modic Changes and Fatty Infiltration in the Paraspinal Muscles at all Lumbar Levels, Except for L1-L2: A Cross-Sectional Analysis of 50 Symptomatic Women and 50 Age-Matched Symptomatic Men World Neurosurgery, Volume 122, 2024, pp. e1069-e1077 Show abstract WebJan 1, 2008 · The objective of this study was to assess the changes of functional integrity of intervertebral disc post fatigue loading. An in vitro biomechanical study using porcine … WebJan 1, 2024 · Biomechanics of the intervertebral disc. The intervertebral disc is subjected to several complex loads arising from different postures and motions during … c spine herniation icd 10