2024 Cullin family protein binding

Cullin family protein binding

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August undefined, 2024

WebMay 23, 2016 · Cullin-2 based E3 ubiquitin ligases, using many different substrate recognition receptors, recognize a number of substrates and regulate their protein … WebApr 12, 2024 · This variant Spry2 behavior, linked to specific stimuli or cell types, seems to depend on its binding to protein phosphatase 2 A (PP2A) and the resulting dephosphorylation of certain residues of ...

The structure and regulation of Cullin 2 based E3 …

WebNov 6, 2024 · Gene ID: 84259, updated on 6-Nov-2024 Summary Enables cullin family protein binding activity. Involved in cellular response to DNA damage stimulus; positive regulation of protein neddylation; and regulation of cell growth. Located in nucleus and spindle. [provided by Alliance of Genome Resources, Apr 2024] Other designations WebMar 21, 2024 · Enables cullin family protein binding activity. Involved in several processes, including negative regulation of G1/S transition of mitotic cell cycle; regulation of protein neddylation; and response to UV-C. Located in nucleus; perinuclear region of cytoplasm; and plasma membrane. [provided by Alliance of Genome Resources, Apr 2024] jesus menocal jr update 2021

AmiGO 2: Term Details for "protein binding" (GO:0005515)

WebApr 12, 2024 · The damaged DNA-binding protein 1 (DDB1) enhances the survival and maintenance of multipotent cells through promoting the Cullin 4 E3 ligase complex-dependent ubiquitination and subsequent degradation of downstream substrates. Naive T cells could be activated and differentiated into effector and memory T cells by exogenous … http://amigo.geneontology.org/amigo/term/GO:0097602 WebMar 21, 2024 · Summary Enables cullin family protein binding activity. Involved in several processes, including negative regulation of G1/S transition of mitotic cell cycle; regulation of protein neddylation; and response to UV-C. Located in nucleus; perinuclear region of cytoplasm; and plasma membrane. [provided by Alliance of Genome Resources, Apr 2024] jesus menino filme

Cullin - Wikipedia

WebApr 27, 2024 · The Cullin-RING ligases (CRL), encompassing Cullin family proteins as scaffold components, are the largest class of RING-type E3 ubiquitin ligases that mediate polyubiquitination of... WebCullin RING ubiquitin E3 ligases (CRL) is the largest family of ubiquitin E3 ligases. In fact, CRL is a multiprotein complex, in which cullin serves as a scaffold linking a ubiquitin … jesus menino shalomWebCullin-4A is a protein that in humans is encoded by the CUL4A gene. CUL4A belongs to the cullin family of ubiquitin ligase proteins and is highly homologous to the CUL4B protein. CUL4A regulates numerous key processes such as DNA repair, chromatin remodeling, spermatogenesis, haematopoiesis and the mitotic cell cycle.As a result, … lampista 24 horas badalona

"WebMay 2, 2016 · We identified that several putative miRNA target genes like Cullin 2 (CUL2), member RAS oncogene family (RAB6A), UBE2I, clathrin heavy chain 1 (CLTC), Desmocollin 3 (DSC3), Ras Family Small GTP Binding Protein (RAP1B), LSM12 homolog (LSM12), protocadherin 11 X-linked (PCDH11X) and HCLS1 Associated Protein X-1 … " - Cullin family protein binding

Cullin family protein binding

31014 - Gene ResultRoc1a Regulator of cullins 1a [ (fruit fly)]

WebNov 24, 2024 · Predicted to enable cullin family protein binding activity. Predicted to be involved in SCF-dependent proteasomal ubiquitin-dependent protein catabolic process. Predicted to be part of SCF ubiquitin ligase complex. Predicted to be active in cytoplasm and nucleus. Orthologous to human SKP1 (S-phase kinase associated protein 1). [provided … WebJun 22, 2007 · CUL3 CRLs use B ric-a-brac, T ramtrack, and B road (BTB) domain-containing proteins that integrate the functions of both adaptor and substrate receptors. A common structural feature shared among the cullin adaptors is the BTB fold, which consists of five α helices separated by three antiparallel β strands.

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WebOct 31, 2024 · Cullin (CUL) proteins have critical roles in development and cancer, however few studies on CUL7 have been reported due to its characteristic molecular … WebGene ID: 83962, updated on 6-Nov-2024 Summary Predicted to enable cullin family protein binding activity and identical protein binding activity. Predicted to be involved in neurogenesis. Predicted to act upstream of or within cell differentiation and muscle organ development. Located in P-body.

WebDec 4, 2024 · Enables cullin family protein binding activity. Involved in positive regulation of protein neddylation. Located in nucleus. [provided by Alliance of Genome Resources, Apr 2024] DCUN1D4 defective in cullin neddylation 1 domain containing 4 [ (human)] WebMembers of this family are small calcium binding proteins containing EF-hand-like domains. They are integral subunit components of native Kv4 channel complexes that …

WebMar 21, 2024 · Enables cullin family protein binding activity. Involved in positive regulation of protein neddylation. Located in cytoplasm and nucleus. [provided by Alliance of Genome Resources, Apr 2024] GeneCards Summary for DCUN1D2 Gene DCUN1D2 (Defective In Cullin Neddylation 1 Domain Containing 2) is a Protein Coding gene. Web(2008) Identifying determinants of cullin binding specificity among the three functionally different Drosophila melanogaster Roc proteins via domain …

WebDec 4, 2011 · Cullin proteins are molecular scaffolds that have crucial roles in the post-translational modification of cellular proteins involving ubiquitin. The mammalian cullin …

WebThe evolutionarily conserved cullin family proteins can assemble as many as 400 distinct E3 ubiquitin ligase complexes that regulate diverse cellular pathways. CUL4, one of three founding cullins conserved from yeast to humans, uses a large beta-propeller protein, DDB1, as a linker to interact with … CRL4s: the CUL4-RING E3 ubiquitin ligases jesus me perdonoWebWerner helicase interacting protein 1 (WRNIP1) is a ubiquitin-binding protein that undergoes extensive post-translational modification including ubiquitination, sumoylation, … lampista 24h badalonaWebMar 21, 2024 · Summary. Enables cullin family protein binding activity. Involved in positive regulation of protein neddylation and regulation of protein ubiquitination. … jesus menocal srWebprotein binding cullin family protein binding (GO:0097602) is_a protein binding dynein heavy chain binding (GO:0045504) is_a protein binding modification-dependent protein binding (GO:0140030) is_a protein binding growth factor binding (GO:0019838) is_a protein binding lampista badalonaWebMay 3, 2024 · We also narrowed down the Cullin family members with the presence of both Cullin and Cullin_Nedd8 domains ... McLoughlin, F.; Vierstra, R.D. Atg8-binding uim proteins define a new class of autophagy adaptors and receptors. Cell 2024, 177, 766–781.e24. [Google Scholar] Marshall, R.S.; McLoughlin, F.; Vierstra, R.D. Autophagic … jesus mercy imageWebIts expression is induced by heat shock. HSP47 is expressed in the endoplasmic reticulum. These cells synthesize and secrete type I and type II collagen. [7] The protein localizes to the endoplasmic reticulum lumen and binds collagen; thus it is thought to be a molecular chaperone involved in the maturation of collagen molecules. lampista manresaWebDec 8, 2024 · Summary Predicted to enable cullin family protein binding activity and ubiquitin-ubiquitin ligase activity. Predicted to contribute to ubiquitin-protein transferase activity. Predicted to be involved in positive regulation of mitotic metaphase/anaphase transition; protein K11-linked ubiquitination; and ubiquitin-dependent protein catabolic … lampista igualada