Hollow mno2 as a tumor-microenvironment
NettetIn this study, we synthesised hollow manganese dioxide nanoparticles (HMDNs) loaded with the hydrophilic chemotherapeutic drug (acriflavine, ACF) and the hydrophobic photosensitizer (chlorine6, Ce6), which was further encapsulated by pH-sensitive liposome to form core-shell nanocomposite, with surface modified with arginine-glycine-aspartic … Nettet27. feb. 2024 · An activatable theranostic platform based on multifunctional MnO 2 -coated mesoporous silica nanoparticles (MS@MnO 2 NPs) has been developed for MRI-monitored combination chemotherapy and chemodynamic therapy (CDT). ADS=antioxidant defense system. Abstract
Hollow mno2 as a tumor-microenvironment
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NettetThe hollow mesoporous MnO2(H-MnO2) nanoshells were obtained after incubating MnO2@SiO2nanoparticles with a Na2CO3solution to dissolve silica. To enhance their … NettetHerein, an intelligent biodegradable hollow manganese dioxide (H-MnO 2 ) nano-platform is developed for not only tumor microenvironment (TME)-specific imaging and on-demand drug release, but also modulation of hypoxic TME to enhance cancer therapy, resulting in comprehensive effects favoring anti-tumor immune responses. With hollow …
Nettet1. mai 2024 · The nanohybrid could efficiently accumulate in tumors through CD44-mediated active targeting. The sequential MnO2-enhanced PDT and efficient NIR-II PTT had a remarkable therapeutic effect by... NettetMnCO can react with the H 2 O 2 to generate CO, powerfully damaging the tumor. Both in vitro and in vivo experiments indicate that the ZCM system is both safe and has …
Nettet14. apr. 2024 · The tumor microenvironment, which includes many cell types such as immune cells, stromal cells, and ECs, ... (2009) owns the copyright to this image. (e) A tubular hollow fiber membrane is included in the kidney-on-a-chip device to mimic the tubular shape of the renal tubule. Hindawi Publishing Corporation (2013) ... Nettet27. apr. 2024 · Tumor microenvironment (TME) is generally featured by low pH values, high glutathione (GSH) concentrations, overproduced hydrogen peroxide (H 2 O 2 ), …
Nettet21. sep. 2024 · A tumor microenvironment responsive biodegradable CaCO 3/MnO 2- based nanoplatform for the enhanced photodynamic therapy and improved PD-L1 …
NettetPeng Xu, 1, 2, * Jia Yao, 1, * Zhen Li, 3, * Meng Wang, 2 Linghui Zhou, 1, 2 Guansheng Zhong, 1 Yi Zheng, 1, 2 Na Li, 1, 2 Zhen Zhai, 1, 2 Si Yang, 1, 2 Ying Wu, 1, 2 Dai Zhang, 2 Zhijun Dai 1 1 Department of Breast Surgery, The First Affiliated Hospital, College of Medicine, Zhejiang University, Hangzhou 310003, People’s Republic of China; 2 … tips for scheduling college classesNettetNational Center for Biotechnology Information tips for saving on heating billsNettet31. mai 2024 · As we all know, the tumor microenvironment is usually characterized by a high glutathione (GSH) concentration, overproduced hydrogen peroxide (H2O2), acidity, and hypoxia, which affect the efficacy of many traditional treatments such as chemotherapy, radiotherapy, and surgery. tips for saving powerNettet27. apr. 2024 · Tumor microenvironment (TME) is generally featured by low pH values, high glutathione (GSH) concentrations, overproduced hydrogen peroxide (H 2 O 2), and severe hypoxia. These characteristics could provide an interior environment for origination and residence of tumor cells and would lead to tumor progression, metastasis, and … tips for saving money on food shoppingNettet7. aug. 2024 · Significantly, the multiple-tumor-microenvironment-responsive features of MnO also provides intelligent MRI and thermal imaging guidance for synergistically enhancing PDT, PTT, and chemotherapy, thus offering an intelligent versatile toolbox for multifunctional nanotheranostic applications. Graphical Abstract Material Advancement … tips for scaffolding children\u0027s learningNettet11. mai 2024 · Yang G, Xu L, Chao Y, et al. Hollow MnO 2 as a tumor-microenvironment-responsive biodegradable nano-platform for combination therapy favoring antitumor immune responses. Nature Communications, 2024, 8 (1): 902 Article CAS Google Scholar tips for saving the planetNettetIn this case, MnO 2 nanosheets serve as (i) a nanocarrier and fluorescence quencher for the photosensitizer Ce6, (ii) a degradable material that is activated by the tumor … tips for scanning photos