Lamp1 if
TīmeklisLAMP1 (CD107a, lysosome-associated membrane protein-1) together with LAMP-2, is a major constituent of lysosomal membrane, 1-2% of total CD107a is found also on the plasma membrane. LAMP1 is a heavily glycosylated membrane protein which contains a putative signal peptide, 18 sites for N-linked glycosylation, a single membrane … Tīmeklislamp1 蛋白羧基末端暴露在细胞浆中，同时它含有一个将 lamp 蛋白靶向至溶酶体膜的酪氨酸分类基序 (4)。lamp1 和 lamp2 的蛋白序列有 37% 同源性。lamp1 和 lamp2 均 …
Lamp1 if
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TīmeklisLAMP1 (CD107a, lysosome-associated membrane protein-1) together with LAMP-2, is a major constituent of lysosomal membrane, 1-2% of … TīmeklisMurine CD107a/LAMP1 (Mr 110-140 kDa with a core protein of Mr ~40 kDa) Tested applications Suitable for: IHC-P, Flow Cyt (Intra) more details Species reactivity Reacts with: Human Immunogen Plasma …
Tīmeklis2024. gada 6. janv. · LAMP1 possesses a large luminal ectodomain and transmembrane domain, followed by a short C-terminal cytoplasmic tail (Fukuda 1991; Eskelinen et al. 2003 ). LAMP1 has a molecular mass of between 90 and 120 kDa, and is heavily glycosylated with a large number of N-glycans and some O-glycans (Fukuda 1991; … Tīmeklis그 결과 연구팀은 쥐의 도파민 신경세포에서 릴린 단백질과 lamp1 리소좀 단백질이 독성 알파시누클레인 단백질을 감소시키는 효과를 확인했다. ...
Lysosomal-associated membrane protein 1 (LAMP-1) also known as lysosome-associated membrane glycoprotein 1 and CD107a (Cluster of Differentiation 107a), is a protein that in humans is encoded by the LAMP1 gene. The human LAMP1 gene is located on the long arm (q) of chromosome 13 at region 3, … Skatīt vairāk Residing primarily across lysosomal membranes, these glycoproteins consist of a large, highly glycosylated end with N-linked carbon chains on the luminal side of the membrane, and a short C-terminal tail exposed to the Skatīt vairāk LAMP1 and LAMP2 glycoproteins comprise 50% of all lysosomal membrane proteins, and are thought to be responsible in part for maintaining lysosomal integrity, pH and catabolism. … Skatīt vairāk • Cluster of differentiation Skatīt vairāk • LAMP1+protein,+human at the U.S. National Library of Medicine Medical Subject Headings (MeSH) • PDBe-KB provides an overview of all the structure information available in the PDB for Human Lysosome-associated membrane glycoprotein 1 Skatīt vairāk LAMP1 expression on the surface of tumor cells has been observed for a number of different cancer types, particularly in highly metastatic cancers such as pancreatic cancer Skatīt vairāk • Chang MH, Karageorgos LE, Meikle PJ (2003). "CD107a (LAMP-1) and CD107b (LAMP-2)". Journal of Biological Regulators and Homeostatic Agents. 16 (2): 147–51. PMID 12144129. • Schleutker J, Haataja L, Renlund M, Puhakka L, Viitala J, Peltonen L, … Skatīt vairāk TīmeklisLAMP1. General description of the gene and the encoded protein (s) using information from HGNC and Ensembl, as well as predictions made by the Human Protein Atlas project. Official gene symbol, which is typically a short form of the gene name, according to HGNC. Full gene name according to HGNC. Assigned HPA protein class (es) for …
Tīmeklis2024. gada 30. apr. · Lamp1 is a transmembrane protein with a large, heavily glycosylated region that faces the lumen of lysosomes. When lysosomes fuse with the plasma membrane, epitopes present on the luminal domain of Lamp1 are exposed on the cell surface. The Lamp1 luminal epitopes can then be detected on the surface of …
Tīmeklis2024. gada 3. sept. · Our study demonstrates that a significant portion of LAMP1-labeled organelles do not contain detectable lysosomal hydrolases including … datediff yy 出生时间 getdateTīmeklis2024. gada 21. marts · LAMP1 Antibody (H4A3) is recommended for detection of LAMP-1 of mouse, rat and human origin by WB, IP, IF, IHC (P) and FCM; also reactive with additional species, including monkey Anti-LAMP1 Antibody (H4A3) is available conjugated to agarose for IP; HRP for WB, IHC (P) and ELISA; and to either … bivalent booster in columbus ohioTīmeklis2016. gada 10. dec. · Varicella-zoster virus (VZV) induces abundant autophagy. Of the nine human herpesviruses, the VZV genome is the smallest (~124 kbp), lacking any known inhibitors of autophagy, such as the herpes simplex virus ICP34.5 neurovirulence gene. Therefore, this review assesses the evidence for VZV-induced cellular stress, … bivalent booster for covid-19TīmeklisLamin B1 (D4Q4Z) Rabbit mAb 可识别核纤层蛋白 B1 总蛋白的内源水平。 本抗体可识别凋亡期间生成的 25 kDa 核纤层蛋白 B1 氨基末端剪切产物。 物种反应性： 人, 小鼠, 大鼠 基于 100% 序列同源性预测发生反应的物种： 用于生产此抗体的抗原序列与此处列出的物种具有 100% 的序列同源性，但 CST 尚未测试或确认其反应性有效。 将本产品 … datedif heuteTīmeklislamp1 蛋白羧基末端暴露在细胞浆中，同时它含有一个将 lamp 蛋白靶向至溶酶体膜的酪氨酸分类基序 (4)。lamp1 和 lamp2 的蛋白序列有 37% 同源性。lamp1 和 lamp2 均在溶酶体-吞噬体融合与胆固醇运输期间参与调节溶酶体的运动性 (5,6)。 bivalent booster if i just had covidTīmeklis2024. gada 13. apr. · The fluorescence intensity of Hsp70.1B was significantly enhanced in Lamp1-positive astrocytes after 6 h of OGD, and RIPK1 knockdown further upregulated the Hsp70.1B levels and enhanced the ... datedif google sheetTīmeklisThe lysosomal membrane proteins LAMP-1 and LAMP-2 are estimated to contribute to about 50% of all proteins of the lysosome membrane. Surprisingly, mice deficient in either LAMP-1 or LAMP-2 are viable and fertile. However, mice deficient in both LAMP-1 and LAMP-2 have an embryonic lethal phenotype. T … bivalent booster in chinese