Web31 Aug 2006 · BECKWITH ROHAN, HOEGENAUER KATE, JENKINS JEREMY LEE, LEHR PHILIPP, ULLRICH THOMAS, WEIGAND KLAUS. Author information. Affiliations. All authors. 1. NOVARTIS AG Application: BR2006PI15614 on 31 Aug 2006 Publication: 31 Aug 2006 PAT: BRPI0615614 . Patent. Share this article Share with ... Web11 Dec 2024 · Structural basis of indisulam-mediated RBM39 recruitment to DCAF15 E3 ligase complex. by Dirksen E Bussiere, Lili Xie, Honnappa Srinivas, Wei Shu, Ashley Burke, Celine Be, Junping Zhao, Adarsh Godbole, Dan King, Rajeshri G Karki, Viktor Hornak, Fangmin Xu, Jennifer Cobb, Nathalie Carte, Andreas O Frank, Alexandra Frommlet, Patrick Graff, …
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Web30 Jan 2024 · Favour A. Akinjiyan, Aleem Fazal, Marc Hild, Rohan E. J. Beckwith, Nathan T. Ross, Joshiawa Paulk, and Seth Carbonneau. SLAS DISCOVERY: Advancing the Science of … WebRohan Beckwith - Novartis Larry Hamann - Celgene/BMS Daniel Simard - Sanofi Adrian Fretland - Astra Zeneca Pia Russo - Astra Zeneca Admin Support NESACS Raj Rajur, Chair Andrew Scholte, past-Chair Anna Singer Saha Ashis blaxland court laidley north
A new druggable step in the gene expression pathway - FMI
WebRohan Beckwith, Xing Dai, Tim Peelen, and Janelle Thompson each read portions of the manuscript and provided a number of helpful comments. Thanks are also due to graduate students Elisa Leonardo and Bryce Sunsdahl at the Livinghouse Laboratory for their invaluable editorial assistance. Thanks also to the anonymous reviewers Web8 Apr 2024 · Discovery of IKZF2/4 degrader DKY709. Pomalidomide (1) (Extended Data Fig. 1a) is a potent IKZF1 degrader (DC 50 10 nM, maximal percent degradation (D max 84%)), but has no effect on IKZF2 protein levels up to 50 µM (Fig. 1a). However, pomalidomide (1) does induce a measurable interaction between IKZF2 and CRBN in cells as measured by a … WebRohan Beckwith, Ph.D. is Vice President of Chemistry at Neomorph bringing over 15 years of experience in Drug Discovery, 7 in the field of targeted protein degradation. blaxland cycles